- A Case of Advanced Hepatocellular Carcinoma Treated with Hepatic Arterial Infusion Chemotherapy
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So Yeon Lee, Si Hyun Bae, Min Su Kim, Jong Young Choi, Seung Kew Yoon, Dong Hoon Lee, Ho Jong Choen
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Journal of the Korean Liver Cancer Study Group. 2006;6(1):52-55. Published online June 30, 2006
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Abstract
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- A 57 year-old-male patient was admitted to our hospital for evaluation of hepatic mass which was detected on
ultrasonography. He had history of chronic hepatitis B and alcoholism. Laboratory findings showed that HBsAg
was positive, and HBeAg was negative. AFP was 5.39 ng/mL. Abdominal CT showed large ill-defined low
density lesion in 4, 7 and 8 segment of the liver with tumor thrombosis at umbilical portion of left portal vein,
which was compatible with advanced hepatocellular carcinoma (stage IVb). Celiac and hepatic arteriogram
revealed huge hypervascular mass at both lobe of the liver. Chemoport catheter was inserted to the right hepatic
artery and intra-arterial chemotherapy (epirubicin 50 mg every 4 weeks, cisplatin 25 mg and 5-FU 200 mg
weekly) was started with continuous infusion device. After 3 cycles of repeated intra-arterial chemotherapy, tumor
mass in both hepatic lobe were decreased in size and extent. He is planned to be treated with additional
intra-arterial chemotherapy.
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